To find the add-on effect of Drakshaadi Avaleha and Gandhakadi Yoga tablets in reducing the frequency of blood transfusions in children with Thalassemia Major.

A study on the add-on effect of Drakshadi Avaleha and Gandhakadi Yoga tablets on the frequency of blood transfusions in Thalassemia Major children a randomised control clinical study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/02/050031

Enrollment

Registered

2023-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D561- Beta thalassemia

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Hb electrophoresis diagnosed cases of Thalassemia major. Parents/guardian willing to give consent to participate in the study.

Exclusion criteria

Exclusion criteria: Cases having HIV, HBV infection, Hepatic failure, DM, TB, malarial infection, active liver disease etc. Other haemoglobinopathies like sickle cell anaemia, hereditary spherocytosis etc. Patients having cardiac and kidney complications. Patients undergone Splenectomy and allogeneic bone marrow transplantation. Known allergy to any content of Drakshadi Avaleha and Gandhakadi Yoga.

Design outcomes

Primary

Measure	Time frame
Reduction in blood transfusion frequency.Timepoint: 0 day, after completion of treatment i.e 3 months and during follow up	—

Secondary

Measure	Time frame
1.Improvement in overall haematocrit value. 2.Reduction in serum ferritin levels. 3.Improvement in quality of life assessed through TranQol scale. Timepoint: 0 day, after completion of treatment i.e 3 months and during follow up	—

Countries

India

Contacts

Public ContactDr Rajagopala S

All India Institute of Ayurveda

srajagopala@gmail.com7600902564

Outcome results