Effect of Bhadradi Kashaya as Oral Administration and as Basti Administration in the Management of Sthula Pramehi(Diabesity) and Obesity

An Experimental controlled clinical study to find the efficacy of Bhadradi kashaya administered orally and as Kala basti in the management of Sthulapramehi (Diabesity)

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/02/050014

Enrollment

Registered

2023-02-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. BMI - >25-35 2.FBS â?? >126-300mg/dl PPBS - >200-380mg/dl 3.HbA1c- >6.5-12 (Patient having classical symptom of sthula and prameha as per ayurvedic text). 4.Waist-hip ratio- Male - > 1 Female >0.86 5. Waist circumference- Male - > 102 cm Female- > 80cm 6.HbA1c-

Exclusion criteria

Exclusion criteria: 1. Patients unfit for Basti Karma. 2. Chronicity: More than 5yrs. 3. Severe systemic diseases like- Pulmonary tuberculosis. Gestational diabetes and malignancy 4. Patients with T2 DM exceeding the following plasma glucose limits- a) Fasting plasma glucose values of >= 300mg/dL b) RBS,PPBS>= 380mg/dL 5. Juvenile Diabetes 6. Insulin dependent Diabetes mellitus 7. Individuals with co-morbidity like HTN (sthula individual)

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of Bhadradi Kashaya when administered Orally and as Basti in the management of Sthula Pramehi (Diabesity)based on clinical parameters(sign and symptoms of Pameha), Biomarker and stool metabolites(SCFAâ??s). â?¢ To evaluate change in body weight and BMI, WHR in the patients of Sthula Pramehi (Diabesity) as well as healthy Obese. Timepoint: 0th,19th,34th day	—

Secondary

Measure	Time frame
To see changes in Gut microbiome diversity To evaluate the quality of life. Timepoint: 0th,19th,34th day	—

Countries

India

Contacts

Public ContactDr Dharam singh

All india institute of ayurveda

santoshbhatted@rediffmail.com9414048459

Outcome results