Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: INDOCYANINE GREEN DOPED WITH CHITOSAN NANOPARTICLES(CNPs-ICG): They will receive aPDT with CNPs-ICG at 1000 µg/mL.
The active solution will be transferred via disposable 3-ml syringe to
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1.Systemically healthy patient 2.Interdental CAL ‘detectable’ at = 2 non-adjacent teeth,33 3.Buccal or oral CAL =3 mm with pocketing >3 mm detectable at =2 teeth 4.Presence of bleeding on probing
Exclusion criteria
Exclusion criteria: •With known systemic illness such as Diabetes mellitus, arthritis and osteoporosis •Patients on systemic medications such as corticosteroids or Calcium channel blockers or taking long-term NSAIDS or taking bisphosphonates or calcium supplements •Use of tobacco in any form and alcohol •History of periodontal therapy in the preceding 6 months •Teeth with Grade-III mobility and/or furcation involvement •Immunocompromised individuals •Pregnant or lactating females •Use of antibiotics in the preceding 6 months which can interfere with bone healing •Tooth with hopeless prognosis •Non-vital tooth with or without periapical pathology •History of radiotherapy therapy in the preceding 1 year in head and neck region
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The outcome variable of the study will be change in Probing depths, Clinical attachment levels, change in modified sulcular bleeding index, and Plaque index and microbiological parameterTimepoint: Baseline to 1 week,1 month and 3 months after aPDT | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in modified sulcular bleeding index, and Plaque index and microbiological parameterTimepoint: Baseline to 1 week,1 month and 3 months after aPDT | — |
Countries
India
Contacts
Public ContactSudip Sen
SCB Dental College and Hospital
Outcome results
None listed