Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: 2mg/kg of actual body weight rounded to the closest 10 mg, at the end of the surgery as a single dose
Control Intervention1: Neostigmine: 70 ug/kg Neostigmine with Glycopyrr
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA I-III physical status patients 2. Who have consented to participate in the study 3. Age- 18-65 years
Exclusion criteria
Exclusion criteria: 1. Chronic kidney disease 2. Chronic liver disease 3. Allergy to study drugs 4. Patients with previously diagnosed lung pathologies- COPD, Asthma, pneumonia or any other known lung pathology. 5. Obese patients 6. Patients with previous thoracic surgery 7. Chest wall deformity 8. Recent surgery under GA in last 30 days 9. Patients with associated chest injury 10. Traumatic brain injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the lung aeration score at 24 hours post operatively.Timepoint: Just before the start of the surgery and 24 hours after the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Length of ICU stay 2. Length of hospital stay 3. 30 day mortality 4. Incidence of tracheostomy during hospital stay 5. POPC till day 7 6. Extubation on table 7. Duration of mechanical ventilation 8. Change in motor power from baseline (at admission) motor power at discharge Timepoint: 30 days | — |
Countries
India
Contacts
Public ContactSumit Roy Chowdhury
Department of Neuroanesthesiology and Critical Care, AIIMS, NEW DELHI
Outcome results
None listed