FindTrial
Sign In

To study the impact of decrease blood supply and oxygen supply to the brain in patients of sepsis, also to compare two different modalities (NIRS and Transcranial Doppler)to correlate the readings of these modalities weather they show the same trends.

Assessment of cerebral perfusion and regional tissue oxygenation (rSO2) using NEAR INFRARED SPECTROSCOPY and TRANSCRANIAL DOPPLER in patients with septic Encephalopathy- An observational prospective study - WILLIS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/02/049920
Enrollment
22
Registered
2023-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R652- Severe sepsis

Interventions

None listed

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with septic encephalopathy admitted in intensive care unit. age more than 18 years either gender.

Exclusion criteria

Exclusion criteria: Patient refuse to consent. Patient those are not a documented case of sepsis. Patient who cannot communicate. Patient having history of neurological illness. Patient having any history of neurological trauma. Patient having any history of Psychiatric illness. Patients having cerebrovascular disease. Patient with alcohol dependance.

Design outcomes

Primary

MeasureTime frame
We are expecting a positive co-relation between indices observed by transcranial doppler for altered cerebral blood flow and rScO2 for regional cerebral tissue oxygenation in patient with sepsis induced encephalopathy.Timepoint: We are expecting a positive co-relation in data observed by two different modality i.e. transcranial doppler for altered cerebral blood flow and rScO2 for regional cerebral tissue oxygenation in patient with sepsis induced encephalopathy at baseline, day1,day2,day3,day4 and day 5.—

Secondary

MeasureTime frame
overall impact of altered blood flow and oxygenation to the brain in terms of altered mental status i. e. decline in baseline GCS, ICU CAM score and MMSE.Timepoint: Assessment of alterations in mental status changes with respect to changes in cerebral tissue oxygenation and cerebral blood flow in Patient of septic encephalopathy with help of GCS, MMSE, ICUCAM score at baseline and day 5.—

Countries

India

Contacts

Public ContactDr Neha Bansal

Dr. Ram Manohar Lohia Institute of Medical Sciences

georgian.manojt@gmail.com7607286685

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026