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To study the role of specific MRI technique in the diagnosis of Parkinson disease and related disorders by comparing imaging findings in patients with those of healthy volunteers or patients suffering from disorders of other system

To evaluate role of Diffusion Tensor Imaging in the diagnosis of Parkinsons disease and Parkinson plus syndrome-A Case Control study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/02/049895
Enrollment
30
Registered
2023-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G250- Essential tremor Health Condition 2: G903- Multi-system degeneration of the autonomic nervous system Health Condition 3: G318- Other specified degenerative diseases of nervous system Health Condition 4: G20- Parkinsons disease Health Condition 5: G231- Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]

Interventions

None listed

Sponsors

Pt B. D. Sharma PGIMS, Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of Idiopathic PD/PD Plus Syndrome of either gender Patients/LAR willing to provide written informed consent

Exclusion criteria

Exclusion criteria: Secondary Parkinsonism by drugs or toxins Cerebrovascular diseases such as cerebral infarction and other CNS disorders

Design outcomes

Primary

MeasureTime frame
To determine neurodegeneration of cortical and subcortical structures by DTI MRI in patients suffering from PD and PD Plus SyndromeTimepoint: 1 year—

Secondary

MeasureTime frame
To determine the effects of severity of disease in Idiopathic PD with neurodegeneration To determine the effects of severity of disease in patients with PD Plus syndromeTimepoint: 1 year—

Countries

India

Contacts

Public ContactDr Keerthan

Pandit B.D. Sharma PGIMS, Rohtak

dragarwalshalini@gmail.com9355622099

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026