To compare the effect of analgesia in two different types of additives to local anesthesia drugs in adductor canal block for lower limb surgeries.

Comparison of analgesic efficacy of Dexamethasone and Dexmedetomidine with 0.5% Ropivacaine in Adductor Canal Block for lower limb surgeries- a prospective randomised controlled study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/02/049884

Enrollment

Registered

2023-02-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S829- Unspecified fracture of lower leg

Interventions

Intervention1: Group A: 15ml of 0.5% ropivacaine plus 2ml of 8mg dexamethasone Control Intervention1: Group B: 15ml of 0.5% Ropivacaine plus 0.5Î¼g/kg of Dexmedetomidine diluted upto a volume of 2ml w

Eligibility

Inclusion criteria

Inclusion criteria: 1)patients with American society of Anesthesiologists(ASA)physical status 1 and 2 2)patients aged between 18 and 60 years 3)patients with BMI more than 20 and less than 30kg/m2 4)informed valid consent of the patient

Exclusion criteria

Exclusion criteria: 1)patients with history of hypersensitivity to local anesthetics 2)history of substance abuse 3)Preexisting neurological diseases like lower extremity neuropathy 4)pregnancy and lactation 5)local infection at the site of block 6)preexisting bleeding disorders and patients on anticoagulant therapy

Design outcomes

Primary

Measure	Time frame
The duration of analgesia(time for rescue analgesia)Timepoint: requirement of rescue analgesia 3,6,12,18,24 hours after adductor canal block given	—

Secondary

Measure	Time frame
Incidence of adverse event like bradycardia ,hypotensionTimepoint: assessment of heart rate and BP 3,6,12,18,24hrs after block given;Numerical rating scale(NRS) scores during rest and movementTimepoint: pain numerically assessed preoperatively and 3,6,12,18,24 hours after block is given postoperatively;Quadriceps motor strengthTimepoint: by straight leg raising test 0-5 scale measured preoperatively and 3,6,12,18,24 hours after block given;Ramsay sedation scoreTimepoint: assessment of sedation from level 1-6- 3,6,12.18,24hrs after block is given;Sensory analgesia by pinprick sensationTimepoint: pinprick sensation over saphenous nerve distribution in lower medial part of leg checked every 5 minutes till 30 minutes after block is given	—

Measure

Time frame

Incidence of adverse event like bradycardia ,hypotensionTimepoint: assessment of heart rate and BP 3,6,12,18,24hrs after block given;Numerical rating scale(NRS) scores during rest and movementTimepoint: pain numerically assessed preoperatively and 3,6,12,18,24 hours after block is given postoperatively;Quadriceps motor strengthTimepoint: by straight leg raising test 0-5 scale measured preoperatively and 3,6,12,18,24 hours after block given;Ramsay sedation scoreTimepoint: assessment of sedation from level 1-6- 3,6,12.18,24hrs after block is given;Sensory analgesia by pinprick sensationTimepoint: pinprick sensation over saphenous nerve distribution in lower medial part of leg checked every 5 minutes till 30 minutes after block is given

—

Countries

India

Contacts

Public ContactDr Jyothi B

karnataka institute of medical sciences

drjyothib1@gmail.com9886187056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026