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Comparison of degree of sedation in hand surgery between two drugs

Comparative Study Of I.V Dexmedetomidine vs I.V Propofol as a Sedative in Patients with brachial plexus block

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049863
Enrollment
70
Registered
2023-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M999- Biomechanical lesion, unspecified Health Condition 2: M849- Disorder of continuity of bone, unspecified Health Condition 3: S529- Unspecified fracture of forearm

Interventions

Intervention1: DEXMEDETOMIDINE AND PROPOFOL FOR SEDATION IN BRACHIAL PLEXUS BLOCK: BOTH DRUGS TO BE GIVEN AT DOSAGE OF DEXMEDETOMIDINE @ 1microgram/kg i.v over 10mins and propofol at dosage of 75micr

Sponsors

Veer Surendra Sai Institute of Medical Science And Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II, 40-80 kg body weight, ASA grade 1 and 2 of both sexes with MPS class 1 and 2 undergoing upper limb surgeries under brachial plexus block were included in the study.

Exclusion criteria

Exclusion criteria: Patients who refused for the study, Patients with failed blocks, Pt with chronic systemic diseases, drug & alcohol abuse, patients allergic to any study medication, patient with 2nd or 3rd degree heart block, Bleeding disorders were excluded from the study.

Design outcomes

Primary

MeasureTime frame
To compare the Sedative property of i.v propofol vs i.v dexmedetomidine based on RAMSAY sedation score and BIS in patients undergoing upper limb surgeries under brachial plexus block.Timepoint: RAMSAY Sedation score and BIS value will be taken every 10 minutes from starting of the surgery till the end of surgery

Secondary

MeasureTime frame
To compare the effect of i.v propofol vs i.v dexmedetomidine for patients undergoing upper limb surgeries under brachial plexus block. And itâ??s effect a) on mean arterial pressure b) on heart rate c) on respiration rate d) on spo2. e) incidence of over and undersedation. Timepoint: AT BASELINE AND EVERY 10MINS TILL END OF SURGERY

Countries

India

Contacts

Public ContactDR DULAL KISHUN SOREN

VIMSAR

drsamir.hota90@gmail.com9348167806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026