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Comparison of two local anaesthetic drugs used epidurally for pain relief after abdominal surgeries.

Comparison of analgesic efficacy of continuous epidural infusion of levobupivacaine with Ropivacaine for postoperative analgesia in onco-surgical patients undergoing exploratory laparotomies.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/02/049852
Enrollment
146
Registered
2023-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

Intervention1: Levobupivacaine: Continuous epidural infusion with levobupivacaine 0.125% for 72hrs. Control Intervention1: Ropivacaine: Continuous epidural infusion with ropivacaine 0.125% for 72hrs.

Sponsors

Dr Rajasree O
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients of either sex between 18â??60 years of age undergoing laparotomies under general anaesthesia with epidural anaesthesia 2.ASA PS I&II 3.Patients who give consent.

Exclusion criteria

Exclusion criteria: 1.Infection at the site of epidural injection. 2.Coagulopathy or bleeding disorders. 3.Raised intracranial pressure, sepsis, pre-existing neurological deficit, demyelinating disorder, or severe spinal deformities. 4.Combined spinal epidural block

Design outcomes

Primary

MeasureTime frame
1.Patient rated Numerical pain rating scale (NRS) 2.Time to first rescue analgesia. 3.Volume of epidural infusion in 72 hours. 4.Total opioid consumption over 72hrs. 5.Adverse effects if anyTimepoint: 4hrs,8hrs,12hrs,16hrs,20hrs,24hrs,28hrs,32hrs,36hrs,40hrs,44hrs,48hrs,52hrs,56hrs,60hrs,64hrs,68hrs,72hrs.—

Secondary

MeasureTime frame
â?¢ To find the total opioid consumption over 72 hours following exploratory laparotomies â?¢ To compare the adverse effects between the two local anaesthetic infusions.Timepoint: 72 hours—

Countries

India

Contacts

Public ContactDr Jaison Lal

Regional Cancer Centre

milisajan@hotmail.com8281227024

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026