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COMPARISON OF EFFECTS OF VARIOUS INFUSION RATES OF THREE INTRAVENOUS ANESTHETIC AGENTS FOR INDUCTION

COMPARISON OF VARIOUS INFUSION RATES ON TWO INTRAVENOUS ANESTHETIC INDUCTION AGENTS IN ADULT SURGICAL PATIENTS COMING FOR VARIOUS SURGICAL PROCEDURES UNDER GENERAL ANESTHESIA IN TERMS OF DOSAGE REQUIREMENT AND HEMODYNAMIC RESPONSE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049822
Enrollment
540
Registered
2023-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z409- Encounter for prophylactic surgery, unspecified Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: INTRAVENOUS INDUCTION USING INFUSION RATES WITH END POINT-LOSS OF VERBAL CONTACT: Total dosage required at infusion rate-500ml/hr,600ml/hr,700ml/hr for propofol and 350ml/hr,400ml/hr,45

Sponsors

SRI RAMACHANDRA INSTITUITE OF HIGHER EDUCATION AND RESEARCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I/II, Elective surgery under general anesthesia more than 1 hour.

Exclusion criteria

Exclusion criteria: patients refusing consent emergency cases, ASA III and above, morbidly obese patients, previous adverse response to general anesthesia, patients recieving medications likely to influence the course of anesthesia or hemodynamic response,eg-antipsychotics, hemodynamically unstable patients.

Design outcomes

Primary

MeasureTime frame
total dosage required and time taken for induction with propofol and etomidate using various infusion rates.Timepoint: at baseline—

Secondary

MeasureTime frame
comparison of hemodynamic parameters between various infusion rates for each drug ,determination ofinfusion rate at which propofol produces similar hemodynamic change as etomidate. Incidence of laryngospasm,myoclonus, injection painTimepoint: at 0 min at induction,3minutes after induction,5minutes after intubation,10minutes after intubation—

Countries

India

Contacts

Public Contactswathi

SRI RAMACHANDRA INSTITUITE OF HIGHER EDUCATION AND RESEARCH

venkymail2014@gmail.com9944731220

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026