Health Condition 1: J989- Respiratory disorder, unspecified Health Condition 2: P220- Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention1: Preterm neonates less than 37 weeks with respiratory Distress started on snippv synchronised nasal intermittent positive pressure ventilation: All infants less than 37 weeks with respir
Sponsors
Nice hospital
Eligibility
Inclusion criteria
Inclusion criteria: All infants less than 37 weeks with respiratory Distress soon after birth and with clinical and radiological diagnosis of RDS
Exclusion criteria
Exclusion criteria: Infants who received respiratory support with either of these modalities prior to randomization Infants with upper airway malformations who are not eligible for non-invasive ventilation Infants who required intubation in delivery room for resuscitation/early intubation within 6 hours of birth. Infants with major congenital malformations (cardiac, lung, airway or others requiring ventilation) Infants with hemodynamic instability at the time of randomization, defined by significant alterations in perfusion, blood pressure or worsening lactate warranting inotropic support.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Need for intubation within 72 hours in RDS neonates who received snippv vs nasal cpapTimepoint: Need for intubation within 72 hours in RDS neonates who received snippv vs nasal cpap | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the outcomes and morbidities before discharge in preterm neonates with RDSTimepoint: Upto 36 weeks post menstrual age | — |
Countries
India
Contacts
Public ContactDr CVS Lakshmi
NICE hospital
Outcome results
None listed