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Comparing two local anaesthestic drugs in C-section under spinal anaesthesia

A comparison and evaluation of hyperbaric Ropivacaine vs hyperbaric Bupivacaine for lower uterine segment caesarean section under spinal anaesthesia â?? Prospective, Randomised control study in Tertiary care hospital, Chengalpattu District, Tamil Nadu

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049800
Enrollment
60
Registered
2023-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: 1- Obstetrics

Interventions

Intervention1: Hyperbaric Ropivacaine: Patient will be administered with 2ml of commercially available hyperbaric 0.75% ROPIVACAINE through spinal anaesthesia for 30 patients in duration of 6 months C

Sponsors

Tagore Medical college and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Caesarean section under ASA II

Exclusion criteria

Exclusion criteria: Patients refusal to participate in the study. Patient who are medical unstable i.e. Patients who come under ASA Grade 3 and above. Known hypersensitivity to any drugs that are to be studied. Failed spinal anaesthesia and general anaesthesia required for previous surgery Presence of Spinal Anaesthesia contra-indications. -Patients on anticoagulants or anti-platelets therapy or patients with Bleeding diathesis or Coagulopathy. -Patients with spine deformity and puncture site infection. -Neurological or Neuromuscular disease.

Design outcomes

Primary

MeasureTime frame
To compare and evaluate the clinical efficacy i.e. the motor and sensory blockade of equal doses of hyperbaric 0.75% Ropivacaine with hyperbaric 0.5% Bupivacaine in LSCS under spinal anaesthesiaTimepoint: Post spinal, every 3 minutes for first 15 minutes, every 5 minutes till end of surgery

Secondary

MeasureTime frame
The hemodynamic changes Pulse rate(PR), systolic blood pressure ( SBP), diastolic blood pressure (DBP) that are caused due to the hyperbaric Ropivacaine in lower segment caesarean section under spinal anaesthesiaTimepoint: Baseline,Pre-spinal,Post spinal every 2 minutes for first 10 minutes, 5 minutes till end of procedure

Countries

India

Contacts

Public ContactDr Shankar Anand

Tagore medical college and hospital

drshankarmed@gmail.com9486476987

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026