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MAGNESIUM SULPHATE VS LIGNOCAINE INTRAVENOUS INFUSION FOR POSTOPERATIVE PAIN RELIEF

A PROSPECTIVE, DOUBLE BLIND, RANDOMIZED CONTROLLED STUDY FOR COMPARING THE EFFICACY OF PERIOPERATIVE I.V LIGNOCAINE VS I.V MAGNESIUM SULFATE INFUSION IN ATTENUATING HEMODYNAMIC PARAMETERS AND POSTOPERATIVE PAIN IN PATIENTS UNDERGOING LAPAROSCOPIC HYSTERECTOMY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049799
Enrollment
150
Registered
2023-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium Sulphate: Loading dose of 30mg/kg of magnesium sulfate followed by a maintanence dose of 15mg/kg/h continous infusion in an iv line until the end of the surgery for 50 patient

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective Laparoscopic Hysterectomy surgery under ASA-PS I&II

Exclusion criteria

Exclusion criteria: Patient who refused to give informed and written consent Patients of ASA-PS III%IV Patients who are allergic to Lignocaine or Magnesium sulfate Patients on opioid medications

Design outcomes

Primary

MeasureTime frame
Postoperative pain assesment by visual analog scale and opioid consumption by the patient in 1st 24Hours of the Post operative periodTimepoint: Immediately after extubation,then Hourly in the first 24Hours

Secondary

MeasureTime frame
Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) will be continuously monitored and recorededTimepoint: pre-op (baseline), pre-induction, post-induction and 1, 3, 5, 10 & 15 minutes after intubation and until the end of the surgery

Countries

India

Contacts

Public ContactDrShankar Anand

Tagore Medical College and Hospital

drshankarmed@gmail.com9486476987

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026