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To compare Hyperbaric Ropivacaine 0.75% And Hyperbaric Bupivacaine 0.5% in spinal anaesthesia For Lower limb Orthopaedic surgeries

A comparative study between Intrathecal Hyperbaric Ropivacaine 0.75% And Hyperbaric Bupivacaine 0.5% For Lower limb Orthopaedic surgeries

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049785
Enrollment
86
Registered
2023-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S799- Unspecified injury of hip and thigh Health Condition 2: S899- Unspecified injury of lower leg

Interventions

Intervention1: Hyperbaric Ropivacaine 0.75% in lower limb orthopaedic surgeries: 3ml of Hyperbaric Ropivacaine 0.75% and Inj Fentanyl 25 mcg intrathecally in lower limb orthopaedic surgeries Control

Sponsors

Teerthankar Mahaveer Medical College and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Written and informed consent American society of anaesthesiologists (ASA) grade I or II patients. Patients scheduled for elective orthopaedic lower limb surgery under spinal anaesthesia. BMI- 18.5 to 24.9 kg/m2

Exclusion criteria

Exclusion criteria: Patients in whom spinal anaesthesia is contraindicated. Local skin infections Severe Back deformities. Coagulopathy, Raised Intracranial Pressure Moderate to severe Valvular Lesions

Design outcomes

Primary

MeasureTime frame
) To assess and compare hemodynamic parameters in between the two groups Hyperbaric Ropivacaine 0.75% and Hyperbaric Bupivacaine 0.5% in spinal anaesthesia. 2) To assess and compare sensory and motor block characteristics between the two groups. 3)To assess and compare the total dose of rescue analgesia needed in 24 hours 4)To assess and compare the quality of intraoperative anaesthesia between the two groups. 5) Side effects and complications will be assessed Timepoint: Hemodynamics- 0,2,4,6,8,10,12,14,20,25 and 30 mins until completion of surgery and every 2hours post operatively until 24 hours VAS score- 0,2,4,8,12,16,20 and 24 hours.—

Secondary

MeasureTime frame
Side effects and complications will be assessedTimepoint: Hemodynamics (HR, RR, SBP, DBP, MAP, SP02)Vitals will be monitored every 2 mins up to 15mins and thereafter every 5 mins until the completion of surgery and postoperatively every two hours till 24 hours—

Countries

India

Contacts

Public ContactDr GS Jheetay

Teerthankar Mahaveer Medical College and Research Centre Moradabad U.P.

drgurdeep.medical@tmu.ac.in8218770729

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026