Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Propofol Ketamine infusion for maintenance of Anaesthesia: In opioid free group ( Group K), Patients will be given Inj. Dexmedetomidine 0.5 mcg/kg[12] bolus dose over 20 minutes prior t
Sponsors
Bhaikaka univercity
Eligibility
Inclusion criteria
Inclusion criteria: patients american society of anesthesiologists .physical status (ASA -PS) I,II,III who can give written and informed consent, Age 18-65 years, either Gender, Patients undergoing elective head and neck cancer surgery
Exclusion criteria
Exclusion criteria: Patients who will not give consent for research ,uncontrolled systemic disease ,conduction abnormality and patient with implantable defibrillator and pacemaker ,who are allergic to study drugs ,h/o convulsion ,psychiatric disorders,renal,hepatic ,cardiac insufficiency ,who will be un-reversed and on mechanical ventilation support post operatively
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the post- operative analgesia in opioid free and opioid containing group of patients undergoing elective head and neck cancer surgeryTimepoint: immediate post-operative period to 1 hr,2,4,8,12,24 hours post-operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare haemodynamic stability in both the groups, To assess and compare post- operative sedation in these two groups of patients. ,To assess the total consumption of drugs, To assess the side effects of drugs.Timepoint: intra operative and post operative 0,1,2,4,6,12,24 hours | — |
Countries
India
Contacts
Public ContactNirali Mavsinh Rathod
Pramukhswami Medical College
Outcome results
None listed