Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system
Conditions
Interventions
Intervention1: Modified response first technique of extubation :Adminstration of reversal of neuromuscular blockade after extubation of the patient: adminstration of neostigmine (0.05mg/kg) and glycop
Sponsors
Post Graduate Institute of medical education and research
Eligibility
Inclusion criteria
Inclusion criteria: Patient undergoing elective supratentorial craniotomy under general anaesthesia after adequate fasting according to standard American Society of Anaesthesiologists (ASA) guidelines Patients belonging to ASA status 1 and 2 Guide : Dr. Hemant Bhagat Professor, Neuroanesthesia, Department of Anesthesia, Post Graduate Institute of Medical education and research email id : hembhagat@rediffmail.com
Exclusion criteria
Exclusion criteria: • Patient refusal for consent • Anticipated difficult airway • History of Obstructive sleep apnea • Pregnancy, achalasia cardia, preexisting acid peptic disease/vocal cord palsy • Uncontrolled diabetes, hypertension, recent respiratory tract infection, bronchial asthma • Patients with pneumocephalus/ pneumoventricle. • Patients with GCS less than 15. • Patients with preexisting involvement of lower cranial nerves.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the quality of emergence score in patients extubated after attainment of consciousness and assessing response just before administration of reversal of neuromuscular block compared to the traditional technique of extubation.Timepoint: The quality of emergence score will be assessed once during extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| The hemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean blood pressure To assess the incidence of Vomiting/regurgitation Aspiration Laryngospasm/bronchospasm Postoperative bleeding into surgical drain for 24 hours Postoperative intracranial hematoma formation using computed tomography scan Neurological outcome at discharge using mRs Timepoint: The same hemodynamic parameters mentioned above will be assessed during the periextubation period i.e., at cessation of anaesthesia followed by continuous monitoring 1 min prior to extubation followed by every 1 minute for 5 mins, every 5 mins upto 15 mins and every 15 mins till one hour post extubation. vomiting and aspiration will be assessed upto 2 hours postoperatively Neurological outcome will be assessed at discharge. | — |
Countries
India
Contacts
Public ContactDr Hemant Bhagat
Post Graduate Institute of Medical Education and Research
Outcome results
None listed