FindTrial
Sign In

A clinical trial to study the role of fractional excretion of urea in chronic liver disease patients with acute kidney failure.

Role of Fractional Excretion of Urea in Determining the Type of Acute Kidney Injury in Decompensated Cirrhosis Patients.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/02/049763
Enrollment
70
Registered
2023-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K74- Fibrosis and cirrhosis of liver

Interventions

None listed

Sponsors

GB Pant Institute of Post graduate Medical education and Research
Lead Sponsor
Prof Ajay Kumar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed cases of cirrhosis having ascites with AKI Stage IB with Serum creatinine more than or equal to 1.5mg/dl

Exclusion criteria

Exclusion criteria: 1) Advanced Chronic Kidney Disease (serum creatinine >4mg/dl) 2) Prior Kidney or Liver Transplant 3) Acute or chronic Renal Replacement Therapy at the time of enrolment 4) Confirmed pregnancy 5) Diagnosed case of Hepatocellular carcinoma 6) Extrahepatic Malignancy 7) Severe Co-morbidities (CHF, COPD)

Design outcomes

Primary

MeasureTime frame
Sensitivity, Specificity, Positive predictive value, Negative predictive value of FEUrea in decompensated cirrhotic patients with Acute Kidney injury for differentiating ATN-AKI vs Non-ATN-AKI.Timepoint: DAY 0 AND DAY 3—

Secondary

MeasureTime frame
Sensitivity, specificity, Positive predictive value, Negative predictive value of FEUrea in decompensated cirrhotic patients with Acute Kidney injury for differentiating HRS-AKI vs Non-HRS-AKI. Sensitivity, specificity, Positive predictive value, Negative predictive value of FEUrea in decompensated cirrhotic patients with Acute Kidney injury for differentiating PRA-AKI vs Non-PRA-AKI.Timepoint: DAY 0 AND DAY 3—

Countries

India

Contacts

Public ContactDr Shabir Ahmad Lone

GB Pant Institute of Post graduate Medical education and Research

ajaykumar.aiims@gmail.com9718599226

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026