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COMPARING CLINICAL EFFICACY OF THREE SUBGINGIVALLY DELIVERED AGENTS FOR TREATMENT OF PERIODONTITIS

EVALUATION OF THREE DIFFERENT SUBGINGIVALLY ADMINISTERED AGENTS FOR NONSURGICAL TREATMENT OF PERIODONTITIS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049742
Enrollment
100
Registered
2023-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: INJECTABLE PLATELET RICH FIBRIN.: SUBGINGIVAL APPLICATION OF INJECTABLE PLATELET RICH FIBRIN IN CHRONIC GENERELIZED PERIODONTITIS PATIENTS Intervention2: SIMVASTATIN GEL 1.2%: SUBGINGIV

Sponsors

VARANASI HARIPRIYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: GOOD ORAL HYGIENE STATUS. GOOD GENERAL HEALTH SUFFERING FROM CHRONIC PERIODONTITIS. PERIODONTAL PROBING POCKET DEPTH MORE THAN OR EQUAL TO 5MM AND CLINICAL ATTACHMENT LOSS MORE THAN 3MM.

Exclusion criteria

Exclusion criteria: PRESENCE OF INTERNAL OR EXTERNAL ROOT RESORPTION. KNOWN ALLERGIES FOR AGENTS USED DURING PROCEDURE. ACUTE OR CHRONIC SYSTEMIC DISORDERS. BLEEDING AND CLOTTING DISORDERS. PREGNANT AND LACTATING MOTHERS.

Design outcomes

Primary

MeasureTime frame
plaque index , sulcus bleeding index , pocket probing depth , clinical attachment loss were recorded at baseline, 1st month and 3rd month after scaling and root planingTimepoint: at baseline, 1st month, 3rd month

Secondary

MeasureTime frame
there was a significant improvement in all four clinical parameters resulting in faster and effective periodontal wound healing and regeneration. none of the experimental groups showed superiority over the other in terms of gingival and periodontal healthTimepoint: at 3rd month

Countries

India

Contacts

Public ContactVARANASI HARIPRIYA

SARDAR PATEL POST GRADUATE INSTITUTE OF DENTAL AND MEDICAL SCIENCES

docamitabh74@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026