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Comparison of addition of a sedative drug Dexmedetomidine in Local Anaesthetic drug Ropivacaine 0.1% concentration mixture with plain Ropivacaine in regional Nerve block given for pain relief after Knee Replacement surgery

comparison of dexmeditomidine as an adjunct to 0.1%ropivacaine to plain ropivacaine in adductor canal block for unilateral total knee replacement:a prospective,double blinded randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049732
Enrollment
64
Registered
2023-02-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: M179- Osteoarthritis of knee, unspecified Health Condition 3: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: 0.1%ropivacaine in adductor canal block: 0.1%ropivacaine will be given through adductor canal catheter after unilateral total knee replacement surgery.The same intervention will be repe

Sponsors

SIR H N RELIANCE FOUNDATION HOSPITAL AND RESEARCH CENTRE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1,2,3 scheduled for unilateral total knee replacement under spinal anesthesia BMI 20-30kg/m2

Exclusion criteria

Exclusion criteria: allergic to any study drugs pregnant patients patients in whom nerve block could not be performed as per methodology patients on pre operative oral opioids patients and or relatives not willing for procedure ASA grade 4 ,age 80yrs BMI >30kg/m2 patients on chronic pain medication any severe perioperative complications

Design outcomes

Primary

MeasureTime frame
To investigate duration of analgesia of ACB using ropivacaine with and without dexmedetomidine after unilateral TKR in first 24 hrs ,both at rest and movingTimepoint: 6hr,12hr,18hr,24hr—

Secondary

MeasureTime frame
to evaluate opioid consumption in first 24 hours of surgeryTimepoint: 6hr,12hr,18hr,24hr—

Countries

India

Contacts

Public ContactSULFATH P

SIR H N RELIANCE FOUNDATION HOSPITAL AND RESEARCH CENTRE

sheetalms@gmail.com9930996594

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026