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Application of LASER along with Indocyanine Green dye as an adjunct to mechanical debridement for treatment of periodontal disease in periodontal maintenance patients.

Indocyanine Green based antimicrobial Photodynamic Therapy as an adjunct to non-surgical periodontal treatment in periodontal maintenance patients: A clinico-microbiological study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049678
Enrollment
25
Registered
2023-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Indocyanine green dye(Aurogreen®, Aurolabs, Madurai, India,1mg/ml) photodynamic therapy as adjunct to Scaling and root planing: Patients will be given Indocyanine green (ICG) based ph

Sponsors

Manipal College Of Dental Sciences, Mangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who agree to participate in the study by signing the informed consent. Age >= 30 years irrespective of gender. Patients diagnosed with stage II and stage III periodontitis having completed active periodontal treatment atleast 3-6 months prior, receiving regularly supportive periodontal therapy (SPT) and exhibiting residual pockets of >=4mm. Systemically healthy controls Full Mouth Plaque Score 25% Full Mouth Bleeding Score 25%

Exclusion criteria

Exclusion criteria: 1. Patients with systemically compromised health like diabetes, that may influence the periodontal status. 2. Use of drugs such as immune-suppressants, anti-epileptic, calcium antagonist 3. Use of antimicrobial mouthrinses in the preceding 2 months 4. Smokers 5. Use of systemic antibiotics in the last twelve months 6. Restorations and superficial caries in the area to be treated. 7. History of allergy of any kind of dye or iodine. 8. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
changes in probing pocket depth and clinical attachment levelTimepoint: 3 months

Secondary

MeasureTime frame
The secondary objective was to compare the changes in detection frequency of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans and Tannerella forsythia, Fusobacterium nucleatum, in subgingival plaque samples of test and control sites before and after therapy.Timepoint: 3 months

Countries

India

Contacts

Public ContactUrbashi Roy Chowdhury

Manipal College of Dental Sciences, Manipal academy of higher education, Mangalore

deepa.gkamath@manipal.edu9448454788

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026