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Effects of two commonly used anaesthetic agents on mitral valve dynamics for left ventricular function assessment using transesophageal echocardiography.

Effects of sevoflurane versus propofol on mitral annular displacement evaluated using speckle tracking.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049598
Enrollment
88
Registered
2023-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: I252- Old myocardial infarction Health Condition 3: I21A- Other type of myocardial infarction

Interventions

Control Intervention1: propofol: In propofol group, 50 t0 100mcg/kg/ min infusion of propofol given throughout the surgery to maintain depth of anesthesia. Control Intervention2: Sevoflurane: Sevoflur

Sponsors

SCTIMST
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Adult patients scheduled for elective CABG under CPB. Age group between 18 â?? 75 years. Normal sinus rhythm.

Exclusion criteria

Exclusion criteria: Patients with other associated complex anomalies. Patients with more than mild MS, MR, AS or AR. Patients with severe mitral annular calcification. Contraindication to TEE probe placement. Patient refusing to participate in the project. Poor 2D & 3D image quality Emergency and Redo surgeries.

Design outcomes

Primary

MeasureTime frame
To study intraoperative differences in MAPSE, mitral annular velocity with TDI and TMAD in CABG patients. To compare effects of sevoflurane and propofol anaesthesia on changes in MAPSE, mitral annular velocity with TDI and TMAD on CABG patients. To compare differences between GLS and MAPSE, mitral annular velocity with TDI and TMAD in CABG patients. Timepoint: intraoperative—

Secondary

MeasureTime frame
To ascertain intraobserver and interobserver variability between TMAD and MAPSE and GLS Timepoint: intraoperative—

Countries

India

Contacts

Public ContactSuda Naveen Kumar

Sree Chitra Tirunal Institute for Medical Sciences and Technology.

shri@sctimst.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026