Health Condition 1: E806- Other disorders of bilirubin metabolism
Conditions
Interventions
Intervention1: Manga Nano (Brand Name) or Manganese Citrate (Generic Name): The intervention being studied is called Manga Nano (Brand Name) or Manganese Citrate (Generic Name), branded by the compa
Sponsors
Prof Asim Kumar Mallick
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria comprised of all the neonates irrespective of the gestational age admitted to the Department of Paediatric Medicine, NRSMH with or without jaundice and those requiring phototherapy to monitor the reduction of bilirubin concentration in the blood with response to the phototherapy. Neonates with neonatal hyperbilirubinemia associated with birth asphyxia. Birth asphyxia is defined if there is presence of at least one of the following condition: A. Gasping or ineffective breathing or lack of breathing at one minute of life B. Need for positive pressure Ventilation for >1minute C. Apgar score [according to the definition mentioned in Facility Based Newborn Care by Government of India]. Neonates with neonatal hyperbilirubinemia associated with ABO incompatibility. ABO incompatibility is defined if there was a mismatch between the blood groups of mother and the newborn. Neonates with neonatal hyperbilirubinemia associated with Rh incompatibility. Rh incompatibility is defined if there was a mismatch between the Rh factors of mother and the newborn. Neonates with neonatal hyperbilirubinemia associated with G6PD deficiency. G6PD deficiency is defined if G6PD levels in blood was
Exclusion criteria
Exclusion criteria: Neonates suffering from Sepsis (defined as a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteraemia in the first week of life.); not suffering from neonatal bilirubinemia, and other co-morbities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome Name: Total Serum Bilirubin concentration in bloodTimepoint: 2 hours, 4 hours, 6 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome Name: Total Serum Bilirubin concentration in bloodTimepoint: 12 hours, 18 hours, 24 hours, 30 hours | — |
Countries
India
Contacts
Public ContactProf Dr Samir Kumar Pal
Chemical, Biological and Macromolecular Sciences, S.N.Bose National Centre for Basic Sciences
Outcome results
None listed