Health Condition 1: K353- Acute appendicitis with localizedperitonitis Health Condition 2: K400- Bilateral inguinal hernia, with obstruction, without gangrene Health Condition 3: T79-T79- Certain early complications of trauma Health Condition 4: N40-N53- Diseases of male genital organs Health Condition 5: M22- Disorder of patella Health Condition 6: M65-M67- Disorders of synovium and tendon Health Condition 7: K41- Femoral hernia Health Condition 8: K40-K46- Hernia Health Condition 9: M00-M02- I
Conditions
Interventions
Intervention1: Hyperbaric 0.5% Levobupivacaine Hydrochloride: Hyperbaric 0.5% Levobupivacaine hydrochloride 2.6 ml with Fentanyl citrate 20 mcg, single neuraxial blockade
Intervention2: Hyperbaric 0.7
Sponsors
Dr Juliet Ann Abraham
Eligibility
Inclusion criteria
Inclusion criteria: ASA I-11 Age 20- 70 years Height 150-180cms Infraumbilical surgeries >2 hours
Exclusion criteria
Exclusion criteria: Patient refusal Local infection Coagulopathies Allergy to the study drugs Any pre-existing neurological deficits Parturients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of onset and duration of motor blockadeTimepoint: The onset of the maximum motor blockade- attaining Grade 4 on the Modified Bromage scale- checked every 3 mins from the time of administration (3 mins, 6 mins, 9 mins, 12 mins) The duration of the motor blockade- from the onset of the motor blockade [(Grade 4 on Modified Bromage scale), peaking at (Modified Bromage scale Grade 1)]till the effect of the drug is completely subsided (Modified Bromage scale Grade 6) - checked every 20 mins post-surgery (20 mins, 40 mins, 60 mins..120mins ) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the onset and duration of sensory blockadeTimepoint: The onset of the sensory blockade - blockade at the level of T10 dermatome - checked every minute from the time of administration of the drug (1 min, 2 min, 3 min, 4 min, 5 min) The duration of the sensory blockade -from the onset of sensory blockade (sensory blockade at T10 dermatomal level) till the requirement of first rescue analgesia (checked every 15 minutes post-op till the 1st hour)- and then every hour till the first 6 hours- 2nd hr, 3rd hr... 6th hour);Comparison of intraoperative hemodynamic profile and occurrence of adverse effects with each study drugTimepoint: Vitals are recorded every two minutes from the time of administration of the drug (0 min, 2 mins, 4 mins...) for the first 20 minutes and then every 5 minutes till the end of the surgical procedure. The adverse effects of each drug are duly noted.;To compare the total consumption of rescue analgesia when the comparator agent and interventional agents are administeredTimepoint: The total consumption of rescue analgesia is determined by the need for intravenous analgesics for the first 6 hours post-surgery (1st hour, 2nd hr...6th hour) | — |
Countries
India
Contacts
Public ContactDr Sam Philip
MOSC Medical College Hospital, Kolenchery
Outcome results
None listed