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To find out effect and safety of polyethylene glycol and sodium hyaluronate in patient with dry eye disease

A comparative study of efficacy and safety of polyethylene glycol and sodium hyaluronate in dry eye disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049510
Enrollment
50
Registered
2023-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H048- Other disorders of lacrimal system

Interventions

Intervention1: Polyethlene glycol: Group-A With Polyethylene glycol 0.1% TDS for 6 weeks Control Intervention1: Sodium Hyaluronate: Group -B Sodium Hyaluronate 0.1% TDS for 6 weeks

Sponsors

Pt BD Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either gender > 18 years of age. Patients diagnosed with moderate dry eye disease (score 9-13) according to Khurana’scoring system. Patients willing to give written informed consent.

Exclusion criteria

Exclusion criteria: Any structural abnormalities Pregnant and lactating women. Hypertension Glaucoma. Diabetes. History of allergy to study medication.

Design outcomes

Primary

MeasureTime frame
1. Schirmer-1 test 2. Tear break-up time (in seconds) 3. Rose Bengal staining score 4. Goblet cellconjunctivalimpression cytologyTimepoint: Safety assessment will be carried out for all the treatment groups at 2 and 6 weeks—

Secondary

MeasureTime frame
1. Fluorescein staining 2. Lissamine green staining 3. Likert scale using standardized facial expressionTimepoint: Safety assessment will be carried out for all the treatment groups at 2 and 6 weeks—

Countries

India

Contacts

Public ContactDr Karthick Sekar

Pt.B.D Sharma PGIMS, Rohtak

karthickronaldo96@gmail.com6385306525

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026