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evaluation of bone biomarker osteocalcin level in gingival fluid in periodontal bony defects which is treated with platelet rich fibrin

Evaluation of Osteocalcin level in Gingival crevicular fluid in Periodontal intrabony defects treated with Autologous Platelet Rich Fibrin - A non randomized experimental study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049488
Enrollment
30
Registered
2023-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Platelet Rich Fibrin: Platelet Rich Fibrin to be placed in the intrabony defect during periodontal flap surgery Control Intervention1: osteocalcin levels: osteocalcin levels are to be c

Sponsors

Dr Sahana S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with stage III grade B periodontitis according to 2017 world workshop on periodontal and peri implant diseases and conditions.Presence of minimum of 16 natural teeth.Molars with the presence of two wall or three wall intrabony defect less than or equal to 3mm as detected on radiography

Exclusion criteria

Exclusion criteria: Medically compromised patients Patients on any medications known to affect the outcomes of periodontal therapy Insufficient platelet count Pregnant or lactating women Smokers or subjects using any form of tobacco Furcation involvement and mobility more than 3mm

Design outcomes

Primary

MeasureTime frame
Improvement in osteocalcin levels Reduction in probing pocket depth Clinical attachment level gain Radiographic bone defect fillTimepoint: baseline, 3 months, 6 months and 9 months

Secondary

MeasureTime frame
Decreased Bleeding on probing Reduction in Plaque index score Timepoint: baseline, 3 months, 6 months and 9 months

Countries

India

Contacts

Public ContactDr Sahana S

Vydehi institute of dental sciences and research centre

docshruthi1984@gmail.com9886824276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026