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comparative study to identify effect levobupivacaine vs bupivacaine in spinal anesthesia for below umbilical surgeries

A comparative study of anesthetic efficacy of 0.5 % Hyperbaric levobupivacaine Vs 0.5 % Hyperbaric bupivacaine for intrathecal anesthesia in below umbilical surgeries- A Prospective Randomized Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049446
Enrollment
80
Registered
2023-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: to study the anesthetic efficacy of levobupivacaine when given intrathecally for spinal anesthesia: 3 ml of 0.5% hyperbaric levobupivacaine total of 15mg will be given once in subarach

Sponsors

sri manakula vinayagar medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients scheduled to undergo elective infra umbilical surgeries under spinal anesthesia for next one year from the date of clearance from Ethical committee. 2. Patients of ASA physical status 1 & 2. 3. Patients of either sex. 4. Age >18 years or 5. Patients with height more than 150 cm

Exclusion criteria

Exclusion criteria: 1. Body Mass Index >30. 2. Patients with local site infection, allergy to the drugs that are to be tested or any othercontraindications for spinal anesthesia. 3. Patients who cannot lie down/ non-co-operative/ psychiatric illness. 4. Alcoholics. 5. Pregnant / Lactating women. 6. Patient having failed spinal, transformed into general anesthesia will be excluded from study. 7. Patients refusal for participation in the study. 8. Patients with height less than 150 cm.

Design outcomes

Primary

MeasureTime frame
To compare the sub-arachnoid block characteristics between 0.5% hyperbaric Levobupivacaine and 0.5% hyperbaric bupivacaine in below umbilical surgeries.Timepoint: to assess the sensory blockade every 2 mins till 20mins to assess the motor blockade every 5mins till maximum level achieved

Secondary

MeasureTime frame
to assess difference in hemodynamic parameter between both the groups to assess the adverse reaction between two groupsTimepoint: 10mins before spinal then at 5 mins every 10 mins for the first half an hour and at 1 hr 2 hrs

Countries

India

Contacts

Public ContactDRSUNEETH P LAZARUS

SRI MANAKULA VINAYAGAR MEDICAL COLLEGE AND HOSPITAL

lazarus.suneeth@gmail.com9894332543

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026