Comparison of effectiveness of Dexmedetomidine in intra operative haemodynamics and post of Analgesia by two different routes in patients who will be posted for Lumbar Spine surgery under General Anaesthesia.

A comparison of Efficacy of Intrathecal Dexmedetomidine versus Intra Venous Dexmedetomidine on intraoperative hemodynamics and postoperative analgesia in patients posted for elective lumbar spine surgeries under General Anesthesia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/02/049416

Enrollment

100

Registered

2023-02-02

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G00-G99- Diseases of the nervous system

Interventions

Intervention1: Intrathecal Dexmedetomidine versus Intravenous Dexmedetomidine in Lumbar spine surgeries: To know the effectiveness of Intrathecal and Intravenous Dexmedetomodine on intra operative hae

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 to 60 years ASA grade I and II Lumbar spine Surgeries under GA

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemodynamic parameters including HR, mean blood pressure (MAP), SpO2 and (Minimal Alveolar Concentration) MAC will be recorded Secondary outcome variables including the postoperative rescue analgesia time, VAS scores and sedation scores will be evaluated. cumulative 24-h Opioid consumption, total intraoperative blood loss will be also recording. Side effects such as Hypotension, bradycardia, nausea, vomiting, shivering and pruritus will be noted and recording.Timepoint: 1.Hemodynamic parameters including HR, mean blood pressure (MAP), SpO2 and (Minimal Alveolar Concentration) MAC will be recorded at base line, at induction and 5, 10, 15, 20, 25, 30, and every 15 min thereafter till end of the procedure . 2.Secondary outcome variables will be evaluated at 1, 2, 4, 8, 12, and 24 h after surgery. The cumulative 24-h Opioid consumption also noted.	—

Measure

Time frame

Hemodynamic parameters including HR, mean blood pressure (MAP), SpO2 and (Minimal Alveolar Concentration) MAC will be recorded Secondary outcome variables including the postoperative rescue analgesia time, VAS scores and sedation scores will be evaluated. cumulative 24-h Opioid consumption, total intraoperative blood loss will be also recording. Side effects such as Hypotension, bradycardia, nausea, vomiting, shivering and pruritus will be noted and recording.Timepoint: 1.Hemodynamic parameters including HR, mean blood pressure (MAP), SpO2 and (Minimal Alveolar Concentration) MAC will be recorded at base line, at induction and 5, 10, 15, 20, 25, 30, and every 15 min thereafter till end of the procedure . 2.Secondary outcome variables will be evaluated at 1, 2, 4, 8, 12, and 24 h after surgery. The cumulative 24-h Opioid consumption also noted.

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Secondary

Measure	Time frame
1. Intraoperative Anesthetics requirement (Opioid and Inhalational agents). 2. Time to extubation after stopping of Inhalational agents. 3. Post operative Sedation evaluated by modified Ramsay Sedation Scale 4. Surgeonâ??s satisfaction with respect to bloodless operative site. As the satisfaction Level of the surgeon based on a Likert scaleTimepoint: the postoperative rescue analgesia time, VAS scores and sedation scores will be evaluated at 1, 2, 4, 8, 12, and 24 h after surgery.	—

Measure

Time frame

1. Intraoperative Anesthetics requirement (Opioid and Inhalational agents). 2. Time to extubation after stopping of Inhalational agents. 3. Post operative Sedation evaluated by modified Ramsay Sedation Scale 4. Surgeonâ??s satisfaction with respect to bloodless operative site. As the satisfaction Level of the surgeon based on a Likert scaleTimepoint: the postoperative rescue analgesia time, VAS scores and sedation scores will be evaluated at 1, 2, 4, 8, 12, and 24 h after surgery.

—

Countries

India

Contacts

Public ContactDr Chandra Sekhar T

PES Institute of Medical Sciences and Research kuppam

dr.chandu24@gmail.com9440042400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026

Comparison of effectiveness of Dexmedetomidine in intra operative haemodynamics and post of Analgesia by two different routes in patients who will be posted for Lumbar Spine surgery under General Anaesthesia.

Conditions

Related papers

Interventions

Sponsors

Eligibility

Inclusion criteria

Exclusion criteria

Design outcomes

Primary

Secondary

Countries

Contacts

Outcome results