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A prospective study to compare the efficacy of empirical Vs tailored therapy in refractory GERD

A prospective study to compare the efficacy of empirical Vs tailored therapy in refractory GERD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049407
Enrollment
70
Registered
2023-02-02
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K210- Gastro-esophageal reflux disease with esophagitis

Interventions

Intervention1: Tailored Drug therapy with known standard drugs: tailoring of any of the following drugs combinations according to investigatory findings, oral route for 2 weeks 1) Tab Dexlansoprazole

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) refractory to PPI therapy for GERD 2) Given written consent and willing to follow up

Exclusion criteria

Exclusion criteria: 1) on drugs which may effect motility of esophagus 2) known cases of carcinoma esophagus 3) known cases of achalasia cardia 4) pregnant women 5) previous history of esophageal surgeries 6) previous history of esophageal endoscopic interventions

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of treatment strategies in refractory GERDTimepoint: after two months of therapy—

Secondary

MeasureTime frame
to describe the spectrum of findings of OGD, HRM, pH monitoring in refractory GERDTimepoint: 2 years—

Countries

India

Contacts

Public ContactDr Mhasisielie Zumu

The Madras Medical Mission Hospital

drarunrs@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026