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Effect of vitamin D supplementation on bone health in children with blood cancer

Effect of vitamin D supplementation during induction phase of chemotherapy on bone mineral homeostasis in children with acute lymphoblastic leukemia: randomized double blind placebo controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/02/049382
Enrollment
80
Registered
2023-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C910- Acute lymphoblastic leukemia [ALL]

Interventions

Intervention1: vitamin D supplementation: Patients with acute lymphoblastic leukemia in the intervention group will receive vitamin D 60000 IU weekly for 6 weeks (total 6 doses) oral starting from day

Sponsors

Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Newly diagnosed patients with acute lymphoblastic leukemia

Exclusion criteria

Exclusion criteria: Relapsed or refractory cases Pre-existing renal disease Pre-existing hepatic disease

Design outcomes

Primary

MeasureTime frame
Change in vitamin D levels at 6 months from baselineTimepoint: 0 and 6 months—

Secondary

MeasureTime frame
Change in serum ICTP levels at 6 months from baseline Change in radiological features at 6 months from baseline Incidence of severe infections during induction of remission Duration of induction of remission Difference in mortality during inductionTimepoint: 0 and 6 months—

Countries

India

Contacts

Public ContactSatyabrata Panda

Institute of Medical Sciences

vineetaguptabhu@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026