Health Condition 1: E113- Type 2 diabetes mellitus with ophthalmic complications
Conditions
Interventions
Intervention1: Vitamin B complex
Vitamin E
α-2 agonist eye drop: Vitamin B complex 1 tablet
Vitamin E 400 mg 1 capsule
α-2 agonist eye drop to eyes 2 times
for 12 months
Control Intervention1: Vi
Sponsors
DHR-ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Indian adult, either sex, with diabetes mellitus Participants must be able to attend all scheduled visits and comply with all trial procedures Signed informed consent form
Exclusion criteria
Exclusion criteria: Participants with diabetic retinopathy (DR) at any stage Presence of ocular disorder (glaucoma, Ealeâ??s disease, branch retinal venous occlusion, etc.) Prediabetes (blood glucose (F) higher than 100 mg/dl but lower than126 mg/dl and blood glucose (PP) higher than 140 mg/dl but lower than 200 mg/dl) Participants with serious comorbidities, like systemic hypertension, cardiovascular, severe renal failure, and neurological abnormalities Participants deprived of liberty, protected adults or vulnerable persons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduce inflammation in retinal neurons of diabetic patients to prevent retinopathy in 12 month Improve retinal microcirculation of diabetic patients to restrict retinopathy in 12 month Timepoint: Reduce inflammation in retinal neurons of diabetic patients to prevent retinopathy in 12 month Improve retinal microcirculation of diabetic patients to restrict retinopathy in 12 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical conditions correlate with development and progression of diabetic retinopathyTimepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Avijit Saha
Deptt of Biochemistry
Outcome results
None listed