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Role of ferritin as a prognostic marker in sepsis.

To study the role of serum ferrtin at admission to PICU as a prognostic marker in paediatric severe sepsis and septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/01/049351
Enrollment
92
Registered
2023-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R798- Other specified abnormal findingsof blood chemistry

Interventions

None listed

Sponsors

Lady Hardinge Medical College and Kalawati Saran Children Hospital, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 6 months to 18 years presenting with severe sepsis and septic shock to PICU

Exclusion criteria

Exclusion criteria: Children with known 1.Multiple blood transfusions 2.Hemoglobinopathies 3.Autoimmune diseases 4.Chronic illnesses like Chronic liver disease, connective tissue disorders

Design outcomes

Primary

MeasureTime frame
Correlation coefficient (r) between serum ferritin levels and PeLOD score in children aged 6 months to 18 years with severe sepsis and septic shock.Timepoint: At admission, at 1 week and at 1 month or at discharge

Secondary

MeasureTime frame
Correlation coefficient (r) between delta (at 1 week) ferritin levels and outcome.Timepoint: At admission, at 1 week and at 1 month or at discharge;Correlation coefficient (r)between ferritin levels within 24 hours of admission with pSOFA score, CRP and Procalcitonin values Timepoint: Within 24 hours of admission to PICU;Prevalence of hyperferritinemia (500ng/ml) in children with paediatric severe sepsis and septic shock.Timepoint: At admission, at 1 week and at 1 month or at discharge

Countries

India

Contacts

Public ContactIsha Kapil

Lady Hardinge Medical College and Kalawati Saran Childrens Hospital

Sguptabhu@gmail.com9779577087

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026