None listed
Conditions
Interventions
Intervention1: VEP will be performed at birth and at 3, 6, 9, and 12 months of chronological age.: VEP will be performed at birth and at 3, 6, 9, and 12 months of chronological age.
Control Interventi
Sponsors
Office of DGAFMS
Eligibility
Inclusion criteria
Inclusion criteria: All neonates delivered at AFMC and Command Hospital (SC), Pune and all infants presenting at 3, 6, 9, and 12 months of age will be included after parental consent.
Exclusion criteria
Exclusion criteria: a) Neonates with perinatal insults including perinatal asphyxia, hypoxia, shock, sepsis, needing respiratory support or any systemic dysfunction b) Neonates/ children with known genetic or chromosomal disorder c) Neonates/ children with clearly identified familial or non-familial syndromes d) Neonates/ infants diagnosed with progressive or neurodegenerative disorders e) Neonates/ infants diagnosed with visual impairment will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is to obtain normative data for the latency and amplitude of the major components of Flash- visual evoked potential in newborn and at 3, 6, 9 and 12 months of life. For the same, The mean, standard deviation and 95% CI for the visual latencies (in ms) and amplitudes (in microvolts) will be determined at all age groups. Graphs plotting the 5th, 50th, and 95th percentile for the various latencies and amplitude of different waveforms of VEP will be generatedTimepoint: The primary outcome of the study is to obtain normative data for the latency and amplitude of the major components of Flash- visual evoked potential in newborn and at 3, 6, 9 and 12 months of life. For the same, The mean, standard deviation and 95% CI for the visual latencies (in ms) and amplitudes (in microvolts) will be determined at all age groups. Graphs plotting the 5th, 50th, and 95th percentile for the various latencies and amplitude of different waveforms of VEP will be generated | — |
Secondary
| Measure | Time frame |
|---|---|
| a) To assess the correlation of gestational age at birth with latency and amplitude of major components of Flash-VEP in newborn b) To assess the correlation of head circumference at birth, 3, 6, 9 and 12 months of life with latency and amplitude of major components of Flash-VEP Timepoint: Flash-VEP in newborns and at 3, 6, 9 and 12 months of life. | — |
Countries
India
Contacts
Public ContactRuchika Jha
Armed Forces Medical College
Outcome results
None listed