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application of guduchi ghrita as eye drop in an allergic eye disease named vernal keratoconjunctivitis.

Clinical efficacy of topical ophthalmic application of Guduchi Ghrita versus sodium chromoglycate 2% eye drops in Vernal Keratoconjunctivitis

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049304
Enrollment
40
Registered
2023-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H108- Other conjunctivitis

Interventions

None listed

Sponsors

Department of Shalakya Tantra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Males or females 4 to 18 years of age. 2. Active VKC 3. Patients were required to have experienced 1 or more recurrences of VKC during the previous year. 4. Only the patients (or patientâ??s guardian) who consent to be included in the study and sign on the consent form attached as annexure 1 will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Patients will be excluded if they demonstrated ocular anomalies other than VKC affecting the ocular surface. 2. Abnormalities of lid anatomic features, nasolacrimal drainage, or blinking function. 3. Active ocular infection or history of ocular herpes, varicella zoster or vaccinia virus infection. 4. Any ocular disease that would require topical ocular treatment during the study. 5. Presence or history of severe systemic allergy at study entry. 6. Topical or systemic corticosteroids within 1 week; topical or systemic immunosuppressive drug within 90 days before enrolment. 7. Scraping of the vernal plaque within 1 month; or any other ocular surgery within 6 months before baseline.

Design outcomes

Primary

MeasureTime frame
Relieve in watering, itching, photophobia and burning sensation Timepoint: The patients will be assessed on 1oth day, 21st day and 30th day after commencing treatment.

Secondary

MeasureTime frame
To compare rescue medicine intake in patients treated with Guduchi Ghrita eye drops or with SCG 2% eye drops in VKC patients. Timepoint: The patients will be assessed on 1oth day, 21st day and 30th day after commencing treatment.

Countries

India

Contacts

Public ContactDr Manoj Kumar

Banaras Hindu University

mkumarbhu@gmail.com9793127744

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026