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Comparision Of The Effects Of Injection Labetolol And Injection Esmolol On Heart Rate And Blood Pressure During Placement Of Artificial Tube Into The Wind Pipe In Patients Undergoing Surgery Under General Anaesthesia

Comparison Of The Effects Of Intravenous Esmolol And Intravenous Labetolol On The Hemodynamic Changes During Laryngoscopy And Intubation In Patients Undergoing Surgery Under General Anesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049299
Enrollment
70
Registered
2023-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Single blinded randomized control study: Comparison of the effects of intravenous esmolol and intravenous labetolol on hemodynamic changes during laryngoscopy and intubation in patients

Sponsors

Dr Vinay Sapare
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient aged 18-50 years of both sexes 2.Patients who require general anaesthesia with oral endotracheal intubation 3.ASA physical status I , II 4.Modified Mallampati class I and II 5.Patients who give informed consent for the study.

Exclusion criteria

Exclusion criteria: 1.Patients with bronchial asthma / cardiovascular diseases 2.Patients on beta blockers 3.Pregnant females. 4.Emergency cases

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of Esmolol and Labetolol in attenuating sympathomimetic response by assessing the hemodynamic changes during laryngoscopy and endotracheal intubation.Timepoint: Baseline, After Induction, After 1 minute, 3 minutes and 5 Minutes after intubation—

Secondary

MeasureTime frame
1)To select the best drug in prevention of sympathomimetic response during laryngoscopy and endotracheal intubation. 2)To describe any adverse events during their use Timepoint: Baseline readings Just after induction 1 minute after intubation 3 minutes after intubation 5 minutes after intubation—

Countries

India

Contacts

Public ContactDr Vinay Sapare

Mandya Institute of Medical Sciences

drkris66@gmail.com9620683953

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026