Comparison of propofol versus ketamine- propofol combination as an anesthetic agent in brain tumors

comparison of propofol versus ketamine- propofol combination as an anesthetic agent in supratentorial tumors: A randomized controlled study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/01/049298

Enrollment

Registered

2023-01-30

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C710- Malignant neoplasm of cerebrum, except lobes and ventricles

Interventions

Intervention1: Endotracheal intubation: Hemodynamic changes Control Intervention1: Administration of ketamine- propofol combination: Administration of ketamine- propofol combination intraoperatively t

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS class 1 and ll Patients undergoing resection of supratentorial brain tumors

Exclusion criteria

Exclusion criteria: Patientsâ?? refusal Pregnant and lactating woman Patients with renal, hepatic or cardiac insufficiency or any endocrinological dysfunction Unconscious patients Increased intracranial pressure BMI >35 kg/ m 2

Design outcomes

Primary

Measure	Time frame
The use of combination of ketamine and propofol is better at maintaining hemodynamic parametersTimepoint: At Pre induction Induction intubation Head pin application Burr hole craniotomy Bone flap removal Dural closure Muscle suture Skin suture During extubation 1 hour postoperative	—

Countries

India

Contacts

Public ContactJakkireddy sravani

AIIMS Raipur

monicakhetrapal@yahoo.com8518881714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026