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To compare the effect of adding dexamethasone with ropivacaine in a block given in back between the muscles using ultrasound for providing pain relief in spine surgeries.

Comparison of effect of dexamethasone as an adjuvant with ropivacaine on pain relief after thoracolumbar interfascial plane block in patients undergoing spine surgeries

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049268
Enrollment
50
Registered
2023-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 0.5% Ropivacaine and dexamethasone: Patients randomized to this group will receive thoracolumbar interfascial plane block with 0.5% ropivacaine (18ml) and 8mg dexamethasone (2ml) follow

Sponsors

Department of Anaesthesia and Intensive Care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) physical status I and II. Patients posted for spine surgery- single level decompression. Age ranging from 18-65 years.

Exclusion criteria

Exclusion criteria: Patient refusal. History of relevant drug allergy. History of psychiatric illness and substance abuse. Patient suffering from severe cardiovascular, respiratory, liver, metabolic or neurological disease. Pregnant patient. Coagulopathy. Infection/ injury at planned injection site. Psychological inability of the patient to understand and interpret visual analogue scale.

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of dexamethasone as an adjuvant with ropivacaine on pain relief after thoracolumbar interfascial plane block in patients undergoing spine surgeries.Timepoint: 24hr

Secondary

MeasureTime frame
Time to first analgesic requirement, total morphine consumption in 24 hours, total rescue analgesic requirement in 24 hours if any, VAS score, side effects if anyTimepoint: 10 mins, 30 mins, 1hr, 4hrs, 8hrs, 12hrs and 24 hr

Countries

India

Contacts

Public ContactDr Richa Saroa

Government Medical College and Hospital, Chandigarh

sanjeev_palta@yahoo.com9646121523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026