effects on postoperative pain after injection of dexmedetomidine on the surgical site in maxillofacial trauma cases

Efficacy of pre-emptive infiltration of dexmedetomidine with local anesthetic on postoperative pain in maxillofacial trauma management under general anesthesia: A double blinded randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/01/049264

Enrollment

Registered

2023-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S024- Fracture of malar, maxillary and zygoma bones Health Condition 2: S026- Fracture of mandible Health Condition 3: S023- Fracture of orbital floor

Interventions

Intervention1: pre emptive infiltration of 1mcg/Kg dexmedetomidine along with 2%lignocaine and 1 :200000 adrenaline: infiltration of dexmedetomidine 1mcg/kg along with local anesthetic(2%lignocaine wi

Eligibility

Inclusion criteria

Inclusion criteria: maxillofacial trauma cases with a VAS score greater than 4 patients consenting to participate in the study patients with ASA1 and ASA2

Exclusion criteria

Exclusion criteria: patients who have known hypersensitivity to lignocaine, dexmedetomidine, fentanyl pregnancy, lactating mothers patients who have a hepatic, renal, or cardiopulmonary abnormality patients with a significant history of head injury patients undergoing conservative management for the maxillofacial trauma

Design outcomes

Primary

Measure	Time frame
to estimate the time taken for the first rescue analgesic used after pre-emptive infiltration of dexmedetomidineTimepoint: 24 hours	—

Secondary

Measure	Time frame
visibility in the surgical fieldTimepoint: 15 min	—

Countries

India

Contacts

Public ContactNaqoosh Haidry

All India Institute of Medical Sciences Patna

aimsrai312@gmail.com8075514228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026