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Study to reduce throat pain and cough by using betamethasone gel and lidocaine jelly in patients with tube inside mouth used to anaesthesia

A COMPARATIVE STUDY OF BETAMETHASONE GEL VERSUS LIDOCAINE JELLY APPLIED OVER ENDOTRACHEAL TUBE TO REDUCE POSTOPERATIVE SORE THROAT,COUGH AND HOARSENESS OF VOICE

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049246
Enrollment
54
Registered
2023-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 0.05% Betamethasone gel: 0.05% betamethasone gel 2.5ml applied over endotracheal tube just before intubation under aseptic precaution Control Intervention1: Lignocaine jelly 2%: 2.5 ml

Sponsors

Dr Smitha B P
Lead Sponsor
Dr Vinay Marulasiddappa
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient willing to give an informed consent. 2) Age between 18-65 years, both genders. 3) ASA grade I and II. 4) Patients undergoing elective surgical procedures, with duration of 90 to 120 minutes, under general anaesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1) Patient not willing to give informed consent. 2) Patients undergoing emergency surgeries. 3) Procedures requiring perioperative nasogastric tube placement. 4) Patients with a high risk of aspiration. 5) Anticipated difficult airway. 6) Pregnant women. 7) Active upper respiratory tract infections. 8) Preoperative sore throat. 9) Previous history of GERD. 10) Head and neck surgeries and surgeries requiring prone position.

Design outcomes

Primary

MeasureTime frame
1) Emergence cough at extubationTimepoint: 1) at extubation that is 0 hr,immediately after surgery

Secondary

MeasureTime frame
1)sore throat 2)cough 3)hoarseness of voiceTimepoint: 1) 1 hour after extubation 2) 24 hours after extubation

Countries

India

Contacts

Public ContactDr Vinay Marulasiddappa

Bangalore Medical College and Research Institute

smithaputtaswamy123@gmail.com9071251863

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026