Protective effect of B Vitamin on the prevention of Diabetic Retinopathy.

Effects of supplementation of B vitamins on the production of mitochondrial-derived peptides (MDPs), lipid peroxidation, lipid-derived protective compounds and inflammation in the pathogenesisof DR

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/01/049218

Enrollment

366

Registered

2023-01-25

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Vit B, Vit E, Vit C: Once a day, oral route. 6 months of interval for 4 years. Intervention2: Vit B, Vit E, Vit C: Once a day Control Intervention1: Vit B, Vit E, Vit C: Once a day, or

Eligibility

Inclusion criteria

Inclusion criteria: Healthy human volunteers

Exclusion criteria

Exclusion criteria: 1. Coronary artery diseases 2. Nepropathy 3. Hypertension 4. Histry of thrombotic event.

Design outcomes

Primary

Measure	Time frame
1. Mesurement of IL-32 2. Mesurement of MDPs like Humanin, MOTS-e. 3.Mesurement of reactive aldehydes. 4. Mesurement of lipid derived protective compound. 5. Mesurement of Vitamin B.Timepoint: 12 hours.	—

Secondary

Measure	Time frame
Vitamin B esetimation propely.Timepoint: 1 (12 hours)	—

Countries

India

Contacts

Public ContactLakshmi Kanta Mondal

Regional Institute of Ophthalmology

lakshmi.mondal62@gmail.com9830830216

Outcome results