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High Frequency Nasal Oxygenation for providing oxygen therapy after abdominal surgeries

A randomised controlled study to evaluate and compare the efficacy of High Frequency Nasal Oxygenation with conventional oxygen therapy for postoperative oxygenation in patients undergoing exploratory laparotomies

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049207
Enrollment
50
Registered
2023-01-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K928- Other specified diseases of the digestive system

Interventions

Intervention1: high flow nasal oxygen therapy: Patients receive HFNO via HFNC in the postoperative period for 24 hrs. Control Intervention1: CONVENTIONAL OXYGEN THERAPY: Patients receive COT via simpl

Sponsors

University College of Medical Sciences and GTB Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting patients scheduled for exploratory abdominal surgeries under general anaesthesia with ARISCAT score >=26 i.e.moderate to high risk.

Exclusion criteria

Exclusion criteria: Chronic obstructive pulmonary disease or asthma causing limitations in everyday activities, heart failure with clinical symptoms equivalent to NYHA functional classification > 2, restrictive lung disease with > 20% reduction in total lung capacity, BMI >40 kg/m2, Inability to comprehend oral or written information

Design outcomes

Primary

MeasureTime frame
PaO2/FiO2 Timepoint: At the end of 24th hr between the two groups

Secondary

MeasureTime frame
PaO2/FiO2, PaCO2, SaO2/FiO2 Patient satisfaction, Chest X ray proven PPC, Proportion of PPCs; Proportion of acute hypoxemic respiratory failure; Reintubation rate or NIV use; Complications associated with interventionTimepoint: PaO2/FiO2, PaCO2 and SaO2/FiO2 at the end of 2nd hr, 6th hr, 12th and 24th hr Patient satisfaction at the end of day 1, Chest X ray proven PPC at the end of day 3

Countries

India

Contacts

Public ContactDr GEETANJALI T CHILKOTI

UNIVERSITY COLLEGE OF MEDICAL SCIENCES, GTB HOSPITAL, DELHI 110095

poonamsehrawat8800@gmail.com9873937636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026