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When to stop luteal support in frozen embryo transfer

Can luteal phase support be stopped at 8 weeks gestation in HRT-FET?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049189
Enrollment
1768
Registered
2023-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O090- Supervision of pregnancy with history of infertility

Interventions

Intervention1: NA: NA Intervention2: NA: NA Intervention3: NA: NA Intervention4: Withdrawal of Luteal Phase Support at completion of 8 weeks gestation: Luteal Phase Support (all forms of progesterone)

Sponsors

Indira IVF Hospital Private Limited
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1) Patients who undergo IVF/ICSI and who have cryopreserved spare embryos. (2) Age 21â??35 years, BMI 21â??30 kg/m2. (3) Patients who undergo SET/DET. (4) A normal uterine cavity was assessed by 3D ultrasound (USG). (5) Recipient of donor oocyte or donor embryo in FET cycle. (6) Embryo transfers of a good quality blastocyst (Gardnerâ??s grade 3/4/5 AA, AB, BA). (7) Endometrial thickness >= 7 mm on day of starting exogenous P4 supplementation. (8) Serum P4 on day of embryo transfer >10ngm/dl.

Exclusion criteria

Exclusion criteria: 1. Patients who undergo Natural cycle FET 2. Patients with more than two failed Embryo Transfer 3. Patients with uterine anomalies, adenomyosis or endometriosis 4. Underlying cardiac or renal or hepatic or thromboembolic disorders or autoimmune disease. (5) History of anxiety or depression. (6) Patients with a history of recurrent 1st-trimester loss

Design outcomes

Secondary

MeasureTime frame
Clinical Pregnancy RateTimepoint: Six weeks after Embryo transfer;Live BirthTimepoint: More than thirty six weeks after embryo transfer;Miscarriage RateTimepoint: Twenty Two after embryo transfer

Primary

MeasureTime frame
Ongoing pregnancy RateTimepoint: Twenty week after embryo transfer

Countries

India

Contacts

Public ContactNihar Ranjan Bhoi

Indira IVF Hospital Private Limited Udaipur

drvipinchandra@indiraivf.in9567971239

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026