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Comparison of bone forming ability of reamer irrigator-aspirator (ria) apparatus with iliac crest bone graft (icbg)

Comparison of osteogenic potential of graft aspirate obtained by reamer irrigator-aspirator (ria) apparatus during intramedullary nailing for femoral shaft fractures with iliac crest bone graft (icbg)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049187
Enrollment
20
Registered
2023-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S723- Fracture of shaft of femur

Interventions

Intervention1: Reamer Irrigator Aspirator: Graft obtained via Reamer Irrigator Aspiration system Intervention2: NIL: NIL Intervention3: Reamer irrigator-aspirator (ria) apparatus: Osteogenic potential

Sponsors

All India Institute of Medical Sciences, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosis of isolated femoral shaft fractures amenable to fixation with an antegrade IM nail 2. Patients with pelviacetabular fractures other fractures or bone grafting procedures necessitating operative intervention 3. Patients giving informed, written consent to be a part of the study

Exclusion criteria

Exclusion criteria: 1. Femoral shaft fractures not amenable to antegrade intramedullary nailing 2. Open fractures 3. Pathological fracture 4. Patients having any of these comorbid conditions: Intracranial events (stroke, bleeding, infection), Fluid or electrolyte disturbances (including dehydration, hyponatremia, Hypernatremia), Acute cardiac events: myocardial infarction, congestive heart failure exacerbation, arrhythmia, Acute pulmonary events: asthma or chronic obstructive pulmonary disease exacerbation, pulmonary embolism, hypoxemia, hypercarbia, on anti coagulants or antiplatelet drugs. - history of leukaemia, cancer with bone metastases, renal failure, patients on dialysis or receiving immunosuppressive medication, and those with suspected local or systemic infection. â?? 5. Patients not giving consent

Design outcomes

Primary

MeasureTime frame
To estimate the release of osteogenic growth factors in the graft aspirate obtained using the reamer irrigator aspirator (RIA) technique for intramedullary nailing of femoral shaft fractures and compare it with that of iliac crest bone graft.Timepoint: From sample taken during surgery (Baseline). No other follow up assesments—

Secondary

MeasureTime frame
NoneTimepoint: NA—

Countries

India

Contacts

Public ContactSamarth Mittal

All India Institute of Medical Sciences, New Delhi

samarthmittal@gmail.com9013562489

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026