Health Condition 1: H171- Central corneal opacity
Conditions
Interventions
Intervention1: changing of the antifungal: 1.Topical Natamycin 5% every half an hourly
2.Oral Ketoconzole 200 mg BD after ruling out associated Liver disease.
3.Atropine eye drop 1% three times a day
Sponsors
L V Prasad Eye Institute
Eligibility
Inclusion criteria
Inclusion criteria: a) Microbiologically proven fungal keratitis with confirmed and significant growth of fungus as per the criteria of significant growth. b) Size of ulcer ranging between 8mm without corneal perforation c) Patients willing to participate and follow up
Exclusion criteria
Exclusion criteria: a) Mixed infections; concomitant fungal, viral or Acanthamoeba infections b) Size of ulcer more than 8 mm c) Impending perforation or presence of corneal perforation at the time of presentation or limbal involvement d) Associated posterior segment involvement or endophthalmitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BCVA, Healing time, Number of corneal ulcers responded on medical treatmentTimepoint: 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients worsened and undergone therapeutic Penetrating keratoplasty (TPK) for worsening of infection.Timepoint: 2 weeks | — |
Countries
India
Contacts
Public ContactDrBhupesh Bagga
L V Prasad Eye Institute
Outcome results
None listed