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ASSOCIATION OF BIOMARKERS IN GCF OF HEALTH, GINGIVITIS, PERIODONTITIS

ESTIMATION AND CORRELATION OF GHRELIN AND OSTEOCALCIN IN GINGIVAL CREVICULAR FLUID OF HEALTH, GENERALIZED GINGIVITIS AND GENERALIZED STAGE III GRADE B PERIODONTITIS â?? A CROSS-SECTIONAL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/01/049155
Enrollment
45
Registered
2023-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

None listed

Sponsors

Madhulika K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals with healthy periodontium. 2. Patients with diagnosis of generalized gingivitis 3. Patients with diagnosis of generalized stage III grade B periodontitis (Periodontal health, gingivitis and periodontitis definition will be based on the classification of periodontal and peri-implant diseases and conditions as proposed in 2017 World Workshop) 4. Individuals with type 2 diabetes mellitus (HbA1c 5. Presence of at least 20 natural teeth

Exclusion criteria

Exclusion criteria: 1. Obese individuals, BMI >25 kg/m2 , waist circumference of >= 90 cm for men and >= 80cm for women according to Asian Pacific Perspective Obesity-WHO 2000. 2. Individuals who have received periodontal therapy in the last 6 months. 3. Individuals with systemic diseases other than type 2 diabetes mellitus (HbA1c 4. Individuals who have history of antimicrobial and anti-inflammatory therapy 5. Smokers 6. Pregnant/lactating and postmenopausal women

Design outcomes

Primary

MeasureTime frame
Biomarkers Ghrelin and OsteocalcinTimepoint: Before treatment

Secondary

MeasureTime frame
Ghrelin and osteocalcinTimepoint: Before treatment

Countries

India

Contacts

Public ContactMadhulika K

The Oxford Dental College

sunaina1096@gmail.com9845203336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026