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To compare reduction in heartrate and blood pressure raise on removal of tracheal tube during general anesthesia by Lignocaine Vs Nalbuphine .

Comparison of attenuation of hemodynamic responses during tracheal extubation by intravenous Lignocaine Vs intravenous Nalbuphine in patients undergoing General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049138
Enrollment
60
Registered
2023-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.Nalbuphine: Patienys under General Anaesthesia post-surgical procedure, , On returning of spontaneous breathing efforts, will receive one of the study drugs(intravenous Nalbuphine

Sponsors

Pondicherry Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: belongs to ASA I, ASA II (American Society of Anesthesiologist classification) Patients undergoing elective surgery under General anesthesia Duration of surgery lasting

Exclusion criteria

Exclusion criteria: 1. Patients undergoing Emergency surgeries 2. Anticipated difficult airway 3. Reduced cardiopulmonary reserves 4. Surgeries confined to larynx and trachea 5. Allergic to Local anesthetics

Design outcomes

Primary

MeasureTime frame
Difference in Mean arterial pressure (MAP),Heart Rate(HR) at 5 minutes after extubation between intravenous lignocaine and intravenous nalbuphine in patients undergoing general anaesthesia .Timepoint: 1. Before extubation 2. One minute after extubation 3. Five minutes after extubation—

Secondary

MeasureTime frame
1.Modified Aldrete recovery score 2.Visual Analogue Score 3.Ramsay Sedation ScoreTimepoint: 1 hour post operatively—

Countries

India

Contacts

Public ContactIndhumathi

Pondicherry Institute Of Medical Sciences,

ramyavel1988@gmail.com9487630425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026