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A Comparative study to evaluate the effect of intravenous fentanyl and nalbuphine on hemodynamic stress response to laryngoscopy and endotracheal intubation in patients undergoing elective surgery under general anesthesia.

A comparative study to evaluate the effect of fentanyl and nalbuphine on hemodynamic stress response to laryngoscopy and endotracheal intubation under general anesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049137
Enrollment
62
Registered
2023-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Endotracheal intubation for general anaesthesia: Intravenous nalbuphine (0.2 mg/kg) versus fentanyl (2 mcg/kg) before endotracheal intubation was given and response to endotracheal intu

Sponsors

Department of Anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients belonging to ASA grade 1 or 2. 2 Patients undergoing elective surgery under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1 Patients refusal for the procedure. 2 Contraindications to general anaesthesia. 3 Patients belonging to ASA grade 3 or above. 4 Patients undergoing emergency surgery. 5 Patients with history of allergy to opioids.

Design outcomes

Primary

MeasureTime frame
To assess the effect of Intravenous fentanyl and nalbuphine on SBP, DBP AND MAP during laryngoscopy and endotracheal intubation.Timepoint: Intra operative during intubation—

Secondary

MeasureTime frame
To assess the effect of Intravenous fentanyl and nalbuphine on heart rate during laryngoscopy and endotracheal intubation.Timepoint: Intra operative during intubation—

Countries

India

Contacts

Public ContactBabita Ramdev

MM Institute of Medical Sciences and Research Centre, Mullana, Ambala

babitaramdev30@gmail.com7888554917

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026