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Comparison of distension of gut between nitrous oxide based and nitrous oxide free general anaesthesia in children less than 28 days of age undergoing open abdominal surgery.

Comparison of bowel distension between nitrous oxide based and nitrous oxide free general anaesthesia in neonates undergoing laparotomy.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/049113
Enrollment
60
Registered
2023-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q410- Congenital absence, atresia and stenosis of duodenum Health Condition 2: Q412- Congenital absence, atresia and stenosis of ileum Health Condition 3: Q411- Congenital absence, atresia and stenosis of jejunum Health Condition 4: Q429- Congenital absence, atresia and stenosis of large intestine, part unspecified Health Condition 5: Q428- Congenital absence, atresia and stenosis of other parts of large intestine Health Condition 6: Q428- Congenital absence, atresia and sten

Interventions

Intervention1: Nitrous oxide effect on bowel distension in neonates undergoing laparatomy: Neonatal patient undergoing laparatomy under general anaesthesia will be given Nitrous Oxide during Intraoper

Sponsors

Vardhman Mahavir Medical College and Safdarjung Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Neonates undergoing laparotomy under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Neonates undergoing surgery for gastroschisis, omphalocele or congenital diaphragmatic hernia 2. Neonates with gangrenous bowel.

Design outcomes

Primary

MeasureTime frame
To compare the severity of intraoperative bowel distension with the use of nitrous oxide free and nitrous oxide based general anaesthesia in neonates undergoing laparotomy using surgical assessment and abdominal girth measurementTimepoint: Measured preoperatively, post induction and then every thirty minutes.

Secondary

MeasureTime frame
To measure vitals like heart, blood pressure and severity of pain and to study corelation between abdominal girth measurement and surgical estimation of abdominal distension.Timepoint: Vitals were measured at every fifteen minutes and pain was assessed every thirty minutes. Abdominal girth was measured preoperative, after induction and postoperatively.

Countries

India

Contacts

Public ContactRanju Gandhi

Vardhman Mahavir medical college and Safdarjung hospital

icu_era@yahoo.co.in9818941341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026