Health Condition 1: K011- Impacted teeth
Conditions
Interventions
Intervention1: Preemptive Montelkast administration: One hour before the procedure, subjects will be given a glass of apple juice in which 10mg montelukast, will be dissolved depending upon their allo
Sponsors
All India Institute Of medical Sciences Mangalagiri
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing surgical extraction of mandibular third molar requiring ostectomy, with or without associated tooth sectioning.
Exclusion criteria
Exclusion criteria: 1.Smokers 2.Pregnant or are breast feeding patients 3.Subjects with confirmed history of allergy to NSAID 4.Subjects with signs of any preoperative inflammatory or infectious condition. 5.Subjects with history of use of NSAIDs within past 21 days. 6.Subjects with presence of periodontal disease, swelling, fever or trismus prior to surgery. 7.Subjects with orthodontic bands on mandibular second molars
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the tissue levels of TNF-aTimepoint: Changes in the tissue levels of TNF-a- before and after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of mouth openingTimepoint: the maximum mouth opening will be measured in the pre- and postoperative periods (after 24 h, 72 h, and 7 days);Intensity of postoperative pain:Timepoint: intensity of their pain at 0, 2, 4, 6, 8, 10, 12, 24, 48, and 72hrs and 7 after surgery;Need of rescue analgesia:Timepoint: use of rescue medication, Ibuprofen 400mg (Brufen 400, Abott pharmaceuticals), including: (1) the time elapsed between the end of the surgical procedure and the requirement of the medicine by the patient; (2) Total dose of rescue analgesic consumed.;Postoperative oedemaTimepoint: The preoperative values and those obtained at 24 h, 72 h, and 7 days after surgery will be analyzed. | — |
Countries
India
Contacts
Public ContactDr Jitendra Chawla
All India Institute of Medical Sciences Mangalagiri
Outcome results
None listed