Health Condition 1: K58- Irritable bowel syndrome
Conditions
Interventions
Intervention1: Lactogut (Multi-strain Probiotic) and Standard Medical Therapy: The treatment period will be for a period of 90 days. During treatment, each participant will receive Lactogut capsules o
Sponsors
Velbiom Probiotics Private Limited
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed case of IBS using Rome III criteria 2. Absence of red flag signs: anemia, fever, weight loss, per rectal bleeding, nocturnal frequency, family history of IBD, cancer 3. Age 18-70 years 4. No synthetic probiotics used in prior 3 months 5. No antibiotics used in previous 2 months of enrolment
Exclusion criteria
Exclusion criteria: 1. Previous treatment with probiotics within last 3 months 2. Pregnant or lactating women 3. History of any previous surgical resection of the stomach, small intestine, or large intestine 4. Complications from infectious enteritis, hyperthyroidism, or hypothyroidism. 5. History of any diet-based intolerance (gluten or lactose intolerance). 6. History of or complications from malignant tumors. 7. Uncontrolled Type II diabetes mellitus. 8. Allergic or sensitive to probiotic products.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessing the effect of multi-strain probiotic on alleviating the symptoms of patients with irritable bowel syndromeTimepoint: 0,7,120,150 and 180 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Monitoring the oral and gut bacteria changes in patients with irritable bowel syndrome before and after treatment with lactogut, through culture dependent, 16S gene sequence and metabolite analysesTimepoint: 0,7,120,150 and 180 days | — |
Countries
India
Contacts
Public ContactDr Shiran Shetty
Manipal Academy of Higher Education
Outcome results
None listed