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EFFECT OF ORAL PREGABALIN ON LARYNGOSCOPY RESPONSE WHEN GIVEN AS PREMEDICATION

EFFECT OF ORAL PREGABALIN AS PREMEDICATION ON LARYNGOSCOPY RESPONSE : A RANDOMISED PLACEBO CONTROL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/01/048997
Enrollment
100
Registered
2023-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pregabalin: TABLET PREGABALIN 150 MG , 1 HOUR BEFORE SURGERY Control Intervention1: placebo: TABLET ( MULTIVITAMIN), 1 HOUR BRFORE SURGERY

Sponsors

MAHARAJA AGRASEN MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I AND II

Exclusion criteria

Exclusion criteria: 1 ASA III and IV 2 Anticipated difficult airway ( Mallampati class III and IV, thyromental distance distance 3 Severe renal disease 4 Allergic to any anaesthetic medication 5 Obese (BMI greater than or equal to 30) 6 ischemic heart disease and major cardiac disorders 7 Patients on β- blockers or vasodilators 8 Patients who will require second attempt of intubation 9 Intubation exceeding 30 seconds

Design outcomes

Primary

MeasureTime frame
To compare the hemodynamic changes during laryngoscopy between patients taking pregabalin (group p) and patients taking placebo (group c).Timepoint: BASELINE(BEFORE MEDICATION), BEFORE INDUCTION , INDUCTION , AFTER LARYNGOSCOPY, 2 MIN , 4 MIN , 6 MIN , 8 MIN , 10 MIN .—

Secondary

MeasureTime frame
intraoperative hemodynamics , analgesic requirementTimepoint: perioperative periods—

Countries

India

Contacts

Public ContactAMANPREET SINGH

MAHARAJA AGRASEN MEDICAL COLLEGE

amanghalot20@gmail.com9991200104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026